When corticosteroid is released directly into the blood stream it causes Increase in serum cholesterol and helps in Sodium and fluid retention, also increases blood sugar level and decrease thyroid hormone levels.
Corticosteroid when released directly into the bloodstream it helps body respond to stress or danger, increase the body's metabolism of glucose and control blood pressure.
Corticosteroids are mainly used to reduce inflammation and suppress the immune system. Corticosteroids modify the functions of epidermal and dermal cells and of leukocytes participating in proliferative and inflammatory skin diseases. After passage through the cell membrane corticosteroids react with receptor proteins in the cytoplasm to form a steroid-receptor complex.
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