Question

Interactions between Na channels and Na -HCO3- cotransporters in the freshwater fish gill MR cell: a model for transepithelial Na uptake

Answer 1

Using intracellular pH (pHi) imaging, we investigated Cl transport mechanisms in freshwater rainbow trout gill mitochondrion-rich (MR) cells. In isolated MR cells, scanning electron microscopy has shown that cellular polarity is maintained.

What is Transport in Two Species of Freshwater Fish?

Large amounts of diluted water constantly flow across the gill epithelium of freshwater fish, causing them to experience an ionic stress. Since the mechanisms of ion and acid-base transport are connected at the gill, this is made worse by an acid-base disruption. Active transport at specialised mitochondrion-rich (MR) cells on the gill surface helps the fish maintain homeostasis. As a result, the freshwater gill has served as a crucial model system for figuring out the transport processes that allow for the overriding of adverse ion gradients. Numerous research have tried to clarify the mechanisms of ion and acid-base transport in freshwater fishes during the past ten years using a range of methodologies.

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