Question

When we ran the serum of a patient who seems to be severely ill with arthritis at the lowest dilution suggested by the latex agglutination kit, the results were negative. what should we do?

Answer 1

The serum sample of the patient should be diluted and ran again before the results are reported to avoid a false-negative result.

What is agglutination?

Agglutination is a process which results when a specific antibody binds to its specific antigen. The antigen-anti-body reaction produces an insoluble complex.

Agglutination reactions are used in agglutination tests which makes use of antibody-antigen reaction to make predictions about certain disease conditions.

Some agglutination tests include blood group tests and arthritis tests.

For the arthritis test, an agglutination that occurs indicates the possibility of arthritis.

The serum sample of the patient should be diluted to avoid a false-negative result due to the prozone phenomenon. This occurs when the concentration of antibody or antigen is too high, thus interfering with the formation of antigen-antibody complex.

In conclusion, agglutination tests are used in testing for diseases.

learn  more about agglutination tests at: brainly.com/question/9825958

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