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8_murik_8 [283]
2 years ago
9

A negative gi side effect associated with non-steroidal anti inflammatory drugs is due to?

Medicine
1 answer:
sergejj [24]2 years ago
6 0

Inhibiting cyclooxygenase-1 (COX-1) enzymes.

NSAIDs are one of the classes of medications that doctors most frequently prescribe. When using NSAIDs, patients frequently have stomach pain, and some of them go on to encounter major gastrointestinal issues such ulceration, bleeding, perforation, or blockage.

The majority of NSAID digestive adverse effects are related to COX inhibition, which lowers prostaglandin levels in the stomach mucosa. Arachidonic acid is transformed into prostaglandin (PG) H2, which is a precursor of PGs and thromboxane, by the enzymes cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2).

These lipid mediators are crucial for both normal physiological processes and inflammatory and painful processes.

Here is another question with an answer similar to this about (COX-1) enzymes: brainly.com/question/19168320

#SPJ4

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What is the equilibrium potential for Na? <br> a. 60 mv <br> b. +60 mv <br> c. -90 mv <br> d. 90 mv
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