Some proteins do indeed need assistance during the folding process. the general term used for the proteins that help other proteins fold is Chaperones.
<h3>What are Chaperones?</h3>
Chaperones are proteins that help big proteins or macromolecular protein complexes fold or unfold conformationally. There are different groups of molecular chaperones, all of which have the same purpose: to help big proteins fold properly during or after synthesis as well as following partial denaturation.
Protein translocation for proteolysis involves chaperones as well. The bulk of molecular chaperones aid in protein folding by binding to and stabilizing folding intermediates up until the polypeptide chain is entirely translated, rather than providing any steric information for protein folding.
Based on their target proteins and location, chaperones have different unique modes of operation.
Learn more about the Protein folding with the help of the given link:
The non-coding strand is also called a template strand which does not code for mRNA where as the strand codes for mRNA are used for furthering the process of transcription
