Importance: Research on the relationship between CYP2C19 genetic variations and the clinical outcomes of individuals with mild stroke or transient ischemic attack who are taking clopidogrel is limited.
The goal is to determine whether CYP2C19 genetic variations are associated with the clinical outcomes of clopidogrel-treated patients who have experienced a mild stroke or transient ischemic attack.
Interventions: In the trial, patients with acute mild ischemic stroke or transient ischemic attack were randomly assigned to receive aspirin alone or clopidogrel in combination with aspirin.
Principal results and metrics The main success result was a new stroke. A composite of new composite vascular events served as the secondary efficacy outcome (ischemic stroke, hemorrhagic stroke, myocardial infarction, or vascular death). The result for safety was bleeding.
The use of clopidogrel plus aspirin compared to aspirin alone decreased the risk of a second stroke only in the subset of patients who were not carriers of the CYP2C19 loss-of-function alleles in patients with mild ischemic stroke or transient ischemic attack. Conclusions and significance. These results suggest that the CYP2C19 genotype contributes to the effectiveness of this therapy.
<h3>What is
transient ischemic attack?</h3>
A stroke known as a transient ischemic attack (TIA) only lasts a short while. When a portion of the brain's blood supply is momentarily cut off, it occurs. Similar to other stroke symptoms, TIA symptoms do not remain as long. Numbness or weakness, especially on one side of the body, are some of the sudden symptoms.
To learn more about transient ischemic attack with the help of given link:
https://brainly.ph/question/13120937
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Answer:
White blood cells (WBCs) are a part of the immune system that helps fight infection and defend the body against other foreign materials. Different types of white blood cells are involved in recognizing intruders, killing harmful bacteria, and creating antibodies to protect your body against future exposure to some bacteria and viruses.
Explanation:
Answer:
Numerical type of evidence.
Explanation:
Numerical type of evidence produced through quantitative research that would be helpful to better understand the selected practice issue. Quantitative research is the process of collecting and analyzing numerical data so we can say that for numerical type of evidence is formed and analyzed with the help of quantitative research and it will help to understand the problem.
“My baby’s dose of Tylenol is based on a healthy adult male.”
Answer:
True
Explanation:
While there is a risk for HBV infection from exposure to mucous membranes or nonintact skin, there is no known risk for HBV infection from exposure to intact skin. The average risk for infection after a needlestick or cut exposure to HCV- infected blood is approximately 1.8%.
