A pleiotropic gene is a genes which determines the multiple traits.
Pleiotropic gene is a single gene which controls more than one phenotypic trait.
Sickle cell allele is an example of the pleiotropic gene.
Pleiotropy was first discovered by Gregor Mendel. Gregor Mendel is known as the Father of the Genetics.
Types of pleiotropy are:
Gene pleiotropy: focused on the number of traits and biochemical factors impacted by a gene.
Developmental pleiotropy: mainly focuses on mutations and their influence on multiple traits.
Selectional pleiotropy: focuses on the number of separate fitness components affected by a gene mutation.
Antagonistic pleiotropy: mainly focuses on the prevalence of gene mutations that have advantages early in life and disadvantages later in life.
More examples of pleiotropic gene are:
Sickle cell anemia: It is a mutation in beta-globin chain results in changes in blood shape and function.
Phenylketonuria: PKU is caused by a mutation of the gene responsible for the production of an enzyme called phenylalanine hydroxylase.
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