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melisa1 [442]
1 year ago
9

olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cance

r: a phase 2, multicentre, open-label, non-randomised study,
Medicine
1 answer:
Serhud [2]1 year ago
8 0

Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer

Why Olaparib is used?

  • To help maintain the response of certain types of ovarian, fallopian tube and peritoneal cancer in people who have completely responded or partially responded to their first or later chemotherapy treatments. For these Olaparib is being used.
  • These tablets are also used to treat certain types of breast cancer that has spread to other parts of the body.
  • These are also used to help maintain the response of a certain type of pancreatic cancer.

what is olaparib used for?

  • Olaparib is used as renovation treatment in patients with superior ovarian most cancers, fallopian tube cancer, or primary peritoneal cancer with a positive type of inherited (germline) or received (somatic) odd BRCA gene

<u>How long can you stay on </u><u>olaparib</u><u>?</u>

  • Median development-loose survival was about 14 months in the placebo organization. Longer comply with-up is wanted to decide median progression-free survival in the olaparib organization, however the modern-day analysis shows it's miles in all likelihood to be longer than 4 years.

To learn more about Olaparib

Visit: brainly.com/question/24263570

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The nurse is preparing to infuse 2 units of packed red blood cells (prbcs) to a client with a gastrointestinal bleed. which acti
ikadub [295]

The nurse needs to be aware about the various blood types, blood transfusion techniques, and reaction monitoring techniques.

Transfusing whole blood or blood components is a component of blood transfusion therapy (BT) (specific portion or fraction of blood lacking in patient). Following a blood transfusion, the patient is susceptible to a number of transfusion-related complications, including graft versus host disease, allergy, febrile (non-hemolytic), and hemolytic responses. Nurse must Check the doctor's order. Inform the client and describe the procedure's goal. Verify the type and cross-matching. To make sure there's a fit Obtain baseline vital readings and record them. adhere to stringent asepsis The label of the blood transfusion is checked by at least two registered nurses.

learn more about blood transfusions here- brainly.com/question/16026147

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5 0
2 years ago
A patient has impacted ear wax in their external auditory canal . What sensory disorder do they have
WINSTONCH [101]

Answer:

tinnitus, conductive hearing loss and aural fullness.

Explanation:

8 0
2 years ago
Questions:
Nimfa-mama [501]
Understanding caries etiology and its progression has been made easy with concomitant advances in science and technology. However, utilization of those advances in community practice is still difficult. Although most of the population in developing countries live in indigence, it is must for the clinician to develop rapid, inexpensive and yet effective methods for caries control and progress. This article provides an insight of how a simple oral rinse test can be used for detection of caries activity.

I think this is correct but I hope it’s helps
3 0
3 years ago
Give an example of a 2 x 2 matrix game with exactly three nash equilibria in pure strategies. Explain.
weeeeeb [17]

Answer:

A Nash equilibrium is a profile of strategies (s1,s2) such that the strategies are best responses to each other, i.e., no player can do strictly better by deviating. This helps us to find the (pure strategy) Nash equilibria.

To start, we find the best response for player 1 for each of the strategies player 2 can play. I will demonstrate this by underlining the best responses:

ABCA1–,10,101–,−10B10–––,01,11,10C−10,110–––,11,1

Player 1 is the row player, player 2 is the column player. If 2 plays column A, then player 1's best response is to play either row A or C, which gives him 1 rather than 0 as payoff. Similarly, the best response to column B is row A, and to column C it is row B.

Now we do the same for player 2 by underlining the best responses of the column player:

ABCA1–,1–0,10–––1–,−10B10–––,01,11,10–––C−10,1–10–––,11,1

So, if player 1 plays row A then player 2 best responds either with column A or column C, giving him 1 rather than 0. We also find the best responses for row B and C.

Now a pure strategy Nash equilibrium is a cell where both payoffs are underlined, i.e., where both strategies are best responses to each other. In the example, the unique pure strategy equilibrium is (A,A). (There may also be mixed strategy equilibria.) In all other cells, at least one player has an incentive to deviate (because it gives him a higher payoff).

EDIT: How to compute mixed strategy equilibria in discrete games?

In a mixed Nash strategy equilibrium, each of the players must be indifferent between any of the pure strategies played with positive probability. If this were not the case, then there is a profitable deviation (play the pure strategy with higher payoff with higher probability).

Consider player 2. He plays column A with probability p, B with probability q, and C with probability 1−p−q. We need to find p,q such that player 1 is indifferent between his pure strategies A,B,C. He is indifferent between row A (left hand side) and row B (right hand side) if p,q are such that

p+10q−10(1−q−p)=q+10(1−p−q).

He is indifferent between B and C if

q+10(1−p−q)=p+q+1−q−p=1.

You just have to solve the first condition for q as function of p, substitute q in the second condition and you have p. Inserting p again in the first gives you q.

Now we do the same with strategies for player 1 such that player 2 is indifferent. Player 1 plays A with probability x, B with probability y and C with probability 1−x−y. The two conditions that follow are

1x+10y−10(1−x−y)=x+10(1−x−y)x+10(1−x−y)=1

Solve this again to find x,y. This is a mixed-strategy equilibrium, because neither player has a profitable deviation. Remember, we constructed the profile (x,y;p,q) such that the other player is indifferent between his pure strategies. So, no matter how the other player unilaterally deviates, his expected payoff will be identical to that in equilibrium (x,y;p,q). In general, depending on the game and solutions x,y,p,q, there may be infinitely many mixed Nash equilibria, or none. The more pure strategies there are, the more tedious it is to compute mixed strategy equilibria, since we solve for N−1 variables for each player (N being the number of pure strategies of the other player).

Moreover, to find all equilibria, if there are more than 2 actions for a player, then every possible combination of actions has to be checked. Here, a player has 3 actions, and a mixed strategy equilibrium could entail mixing over all three or just any two of them. Since such a player would not have to be indifferent regarding the strategy played with probability 0, the equations you have to set up are different. In summary, manually checking for all possible mixed strategy equilibria if at least one player has more than two actions can require a lot of effort.

mark me brainliest

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4 0
2 years ago
_____ are the leading cause of poisoning in young children. a. different types of food b. hand sanitizer c. art supplies d. plan
Vinvika [58]

Answer:

I think its different types of food, which is a.

8 0
3 years ago
Read 2 more answers
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