<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
</span>
Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
Vast away of industries, like the other person said they said more
Answer:
It would affect the functionality of the other levels including the organism
Explanation:
The level of biological organization is a hierarchical step consisting of how a multicellular organism forms. According to this level of organization, CELLS are the simplest unit of life and the collection of cells with a similar function is termed TISSUE. Tissues form ORGANS, organs form ORGAN SYSTEMS and finally, a collection of all the systems in the body forms the ORGANISM.
Based on this, one would observe that each level is related to the next in such a way that one forms from the other. Hence, if one of the levels in the biological organization will not perform its function properly, the other levels will be affected. For example, if the kidney cells do not perform it's function, it would affect the functionality of the kidney tissues, kidney organ, the excretory system, and the organism at large.
