a. The error rate of DNA replication is 1.0 × 10^-8 per base pair. This is considering that a human has approximately 3 billion base pairs where mutations can occur. However, this mutation is kept low by the proof-reading mechanism of DNA polymerases which are 99% efficient.
b. Given that the human genome is 3.2 × 109 bp, this means that there are on average 0.32 new substitutions every time the complete genome is replicated. In humans, there are about 30 cell generations between zygote and egg cells and about 400 cell divisions between a zygote and mature sperm. Thus, in males, the sperm cells have about 128 new mutations and the haploid egg genome has about 10 new mutations for a total of 138 new mutations in every new zygote.
c. Considering the above-mentioned mutation rates of approximately 1 and 2 mutations per 100 million base pairs between generations, then there will be approximately 130 mutations per generation. This means I will probably have about 130 different nucleotide bases from that of my parents.
<span>d. Siblings at an average of 50%, grandparents at an average of 25%; aunts/ uncles at an average of 25%; and first cousins at 12.5%.
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<span>f. You are approximately different from the other random person by one SNP per 1000 bases. The human genome is about 3 Gbps long and therefore about 3 million SNPs among two random people.</span> With about 20,000 genes each having a coding sequence (exons) about 1.5 kb long (i.e. about 500 amino acids long protein on average), the human coding sequence covers 30 Mbp or about 1 percent of the genome. If SNPs were randomly distributed along the genome that will suggest about 30,000 SNP across the genome coding sequence or just over 1 per gene coding sequence.
g. Humans carry on average one to two mutations that, if inherited from both parents, can cause severe genetic disorders or death before reaching reproductive age. These mutations are what are referred to as recessive alleles of a gene.
<span>h. Mosaicism refers to individuals with genetically distinct cell lines that originated from a single zygote, whereas chimerism refers to those who originated from more than one zygote. Microchimerism is the co-existence of two genetically different cell populations in one organism, of which one occurs in a very low number. </span>
Answer:
Chromosomes are systemized structures of proteins and DNA. It have a string like shape, mainly located within the nucleus of both plant and animal cells. DNA is concentrated in the chromosomes. In 1902, Sutton and Boveri proposed that chromosomes has a part in heredity opposing Mendel's theory of segregation and independent assortment.
One major function of the chromosome is to keep the DNA from being altered or negatively influenced during cell division. It ensures accurate distribution of the DNA during the breaking down of genetic material. In mitosis, the chromosomes are duplicated and dispersed to daughter cells so that each cell attains a diploid set of chromosomes totally of the same nature to that of its parent cell. In meiosis, the resultant cells would attain a chromosome from each chromosome pair this will lead to half the number of chromosomes. This process is important for the offspring being produced to have the same characteristics of the parents which would results from the fusion of the sperm and egg of the parents.
Answer:
The breathing rate increases.
Answer:
Please find the explanation below
Explanation:
Sexual reproduction is the kind of reproduction that requires two organisms (male and female) to form an offspring. The male organism produces gametes called SPERM while the female organism produces gametes called EGG. These two gametes come together in a process called FERTILIZATION to produce a zygote, which develops into an offspring.
In sexual reproduction, gametes are produced by organisms involved via a process called MEIOSIS. Meiosis, however, reduces the chromosome number of the gametes by half. However, one process unique to only meiosis and sexual reproduction is called CROSSING OVER.
Crossing over is the process whereby chromosome segments is exchanged between non-sister chromatids of homologous chromosome. This process causes a recombination of chromosomes (alleles) in such a way that the gametes will be genetically different from the parent organisms (genetic variation). According to this question, sexual reproduction leads to more genetic variation than asexual reproduction due to the process of CROSSING OVER that occurs in sexual reproduction.
