Question

after a power stroke, the myosin head must detach from acting before another powerstroke can occur. what causes

Answer 1

The myosin head separates from actin as a result of ATP binding. The intrinsic ATPase activity of myosin then transforms ATP into ADP and Pi. The myosin head's angle is altered into a cocked state by the energy generated during ATP hydrolysis. The myosin head is now ready to move in the future.

The myosin protein is in a high-energy conformation when the head is cocked. At the end of the power stroke, the myosin head is in a low-energy position because this energy has been used up during the power stroke. ADP is released following the power stroke, but the cross-bridge is still there and actin and myosin are joined together.

Since ATP is readily available, the cross-bridge cycle can repeat, and muscular contraction can go on as long as ATP is there.

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