Answer:
The easiest argument is the next one:
Suppose phytochemicals are like money. If I put you in a phone cabin with a lot of money and give you 30 sec to be there collecting as much money as you can, at the end you will collect not all the money and a lot of money will be lost. The same happens whit phytochemicals in supplements there are so many that your body can't use them all.
And other thing is that phytochemicals in supplements comes so concentrated that your body will be overstimulated to take this phytochemicals and that changes your normal digestion, in the time it may looks good...but if you don't take supplements anymore, your body will feel the lost and the physical results would be awull.
Jackals were one of the most breaded animal for fur coats in the 19th century
Answer:
A few obstacles would make it tough to accomplish this objective. In the first place, the polypeptide backbone is characteristically polar. Hardly any proteins would be dissolvable in a non-polar hydrocarbon. Moreover, to keep up the dissolvability of this protein, most of its amino acids would need to contain hydrophobic or non-polar R groups.
Then again, its charged or polar R groups would need to connect with one another or be covered in the core of the protein away from the hydrocarbon solvent. This would put noteworthy requirements on both the idea of the R groups and the structure of the protein that could take part in substrate recognition or catalysis. By and large, this is certainly not a reasonable objective.
Answer with Explanation:
Gramicidine is an antibiotic that has a polypeptide structure and is composed of 3 chains. This molecule can adopt a structure called beta 6-3 helix, so as to form a channel through the cell membrane of bacteria which allows the passage of ions (in this case cations) such as H +, K + or Na +, this situation leads to that in the cell alterations in the content of cellular cations are generated, among the effects the loss of potassium that can cause the death of the cell due to hemolysis due to alteration in the permeability of the membrane is highlighted. This effect is known as the ionophore effect.
An ionophore effect leads to the inhibition in the release of H + to the mitochondrial electronic transport chain.
Gramicidin thanks to its mechanism of action, when it produces interference specifically in a cellular organelle called mitochondria in the inner mitochondrial membrane, it is responsible for interrupting the passage of electrons, alters the gradient of H + and the performance of the enzyme called ATP- synthase which is responsible for producing ATP.
The damage that the entire previous situation produces on oxidative phosphorylation, leads to the refusal of ADP refosphorylation, then ADP and its hydrolysis products will accumulate, and finally the result will be a decrease in ATP levels.
