Question

Are children of a crystic fibrosis carrier and someone with two affected alleles likely to have crystic fibrosis?

Answer 1

Children of CF carriers can inherit their copy of the CFTR gene mutation. There is a 25% (1 in 4) probability that a child born to two CF carriers will have the disease.

What causes cystic fibrosis primarily?

• Cystic fibrosis is brought on by a mutation in the CFTR gene (cystic fibrosis transmembrane conductance regulator).
• This gene regulates the movement of fluids and salt into and out of your cells.
• When the CFTR gene isn't functioning properly, your body produces a buildup of sticky mucus.

Cystic fibrosis usually results in death.

• When cystic fibrosis causes a severe illness or the lungs stop functioning properly, it can be fatal.
• It also has a tendency to get worse over time. However, because to improvements in medicine, patients with cystic fibrosis are now living longer.
• Approximately half of those who have cystic fibrosis will live past the age of 40 at this time.

learn more about crystic fibrosis here

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