Question

development of neuron-astrocyte co-culture system for mechanistic and pharmacological studies in neurodegeneration

Answer 1

Neurodegenerative disorders like Alzheimer's disease and Parkinson's disease are characterized by the progressive atrophy and loss of neuronal function.

• Lack of knowledge of the essential molecular pathways that cause neurodegeneration is one of the major barriers to the development of neuroprotective medicines for Parkinson's disease and other neurodegenerative illnesses.
• A deeper understanding of the diseases' molecular processes is urgently required.
• The lack of suitable in vitro models is a significant barrier to the creation of innovative neuroprotective therapies and the identification of early illness biomarkers.
• Furthermore, the majority of the ones that are available do not have active neuron-glia interactions. However, it is generally known that astrocytes are essential to both a healthy brain and to pathology, therefore their absence affects the applicability of these models.

Learn more about the neurodegenration with the help of the given link:

brainly.com/question/13047924

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