A form of neuraxial anesthesia known as spinal anesthesia involves injecting local anesthetic (LA) into the cerebrospinal fluid (CSF) of the lumbar spine in order to numb the nerves that leave the spinal cord.
<h3>What does the study indicate?</h3>
As long as there is no indwelling epidural catheter or neuraxial anesthesia contraindication, spinal anesthesia is generally regarded as a reasonable anesthetic choice for cesarean delivery in severe preeclampsia.
Those with severe preeclampsia experience spinal-induced hypotension less frequently and with less severity than healthy parturients.
Although spinal anesthetic may result in more hypotension than epidural anesthesia in cases of severe preeclampsia, this hypotension is often manageable, transient, and unrelated to clinically meaningful differences in outcomes.
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Temperature can cause an enzymes shape and function to alter due to the fact that once an enzyme reaches its optimum level, if it goes over it begins to denature. If the temperature is below optimum, then an enzyme will work at a slower rate. Also, the pH can affect an enzyme.