Cytotoxic T (Tc) cells carry both TCR and CD8 receptors.
Why is Cytotoxic T (Tc) cells important?
An essential subset of T cells called cytotoxic T cells reacts to intracellular infections caused by viruses and cancerous cells. These cells can control the infection by directly eradicating infected cells since they have CD8 molecules on their cell surfaces.
Which cells are cytotoxic T cells?
Effector cells known as cytotoxic T cells are responsible for eliminating tumor cells, tissue transplants, and virus-infected cells that are present in the cytosol, or adjacent nuclear compartment. Since the cells display the CD8 glycoprotein on their surfaces and are linked to MHC class I molecules, they are also referred to as CD8+ T cells.
What does the TCR of a CD8 T cells interact with?
As a result, the closeness of CD8 and TCR, which interact with pMHC at the very beginning stages of Ag recognition, is believed to control the T cell sensitivity. The way that TCR and CD8 interact with pMHC differs substantially.
Learn more about Cytotoxic T (Tc) cells: brainly.com/question/4116579
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