Answer:
a. substantia nigra
b. substantia nigra (it is repeated)
Explanation:
Parkinson's disease is a neurodegenerative disease that is caused by the death of neurons that release the neurotransmitter dopamine in the <u>substantia nigra</u>, or locus niger, -a region of the brain that regulates brain circuits that give the 'orders' to initiate voluntary movements- .
The lack of this neurotransmitter leads to the occurrence of the main symptoms suffered by patients: decreased movements, muscle stiffness, postural instability and tremor. These failures are generated by the abnormal way in which neurons work in the absence of dopamine through a mechanism that is not known in depth.
It is the second most frequent neurodegenerative disease, after Alzheimer's disease, with a prevalence of 2% in people over 65 years. The characteristic symptoms of stiffness, bradykinesia and tremor are associated with losses of neurons in the substantia nigra and dopamine depletion in the striatum. There are large cytoplasmic inclusions, called Lewy bodies, which are the pathological mark of the disease and appear predominantly in neurons that contain melanin of the nigra substance. Genetic studies in a subgroup of families with Parkinson's disease with autosomal dominant inheritance found a locus on chromosome 4q-21 23 and a mutation in the gene that encodes a synaptic protein, α-synuclein.
The answers is chromosomes
Answer: B
Explanation:
Ammonia is so toxic that it can be transported and excreted only in large volumes of very dilute solution. As a result most terrestrial animals simply don't have access to sufficient water to routine excrete ammonia.
The main advantage of urea is its very low toxicity. Animals can transport urea in the circulatory system and store it safely in high concentrations. Also much less water is loss when a given quantity of nitrogen is excreted in a concentrated solution of urea than would be in a dilute solution of ammonia.
Answer:
my gut is telling me A because histamine sound familiar
