This is best illustrated by the fact that the blood-brain barrier breaks down begining in the Hippocampus<span>. Deep inside the medial temporal lobe is the region of the brain known as the limbic system which includes the hippocampus, the amygdala, the cingulate gyrus, the thalamus, the hypothalamus, mammillary body; many of which are important to the processing of memory. The Hippocampus is the region of the brain is responsible for learning and memory. The breakdown of the blood brain barrier causes an increase in neurotoxins in the cerebral spinal fluids hence causing progressive degeneration of brain neurons. </span>
The blood-brain barrier is important for the normal functioning and information processing in the brain as it limits the entry of any products, pathogens, and cells present in the blood into the brain.
Hippocampus is a region of the brain that plays a role in learning and memory and it is this region that the break down of blood-brain barrier begins as the early sign of ageing.
