Answer:
The Various Kinases that is activated after the breaks in DNA is after the activation of ATM serine threonine kinase which helps in phosphorylation of other DNA replication check proteins, p53 protein (tumor suppressor protein) etc.
Explanation:
ATM activated by MRN complex at the site of DNA double stranded breaks by phosphorylation. MRN complex activity on ATM induces a conformational change in ATM kinase. So it can bind to its various substrate molecules that helps in DNA replication cycle arrest.
ATM phosphorylates CHK2 protein a product of CHEK2 gene, also known as effector kinases that phosphorylates and helps in deactivation of cyclin dependent kinases (CDKs) that helps in the prevention of progression of mitotic phase.
ATM also phosphorylates the inhibitors of p53 proteins which leads to the overexpression of p21, an inhibitor of (CDKs).
The answer is<span> the tetrahedron.</span>
The answer to this question would be: excess fluoride intake
The toothpaste has a high amount of fluoride and will increase the blood fluor level. Excess fluoride intake in children can cause fluorosis which was the brown staining of teeth because fluor is deposited in the growing teeth. Fluorosis can happen in children with <8-year ages.
<u>Answer:</u>
<em>The true statement concerning complex multi-cellular organism is Bulk transport systems move substances faster than simple diffusion.</em>
<u>Explanation:</u>
<em>Bulk transport</em> is the mechanism that is used by the cells to transport the large quantity of small and tiny molecules and particles. Bulk transport works on the <em>mechanism of pressure gradient and single diffusion</em> is based on the concentration gradient.
The<em> transportation on single diffusion</em> is due to random motion of molecules but in bulk transport the solute and water is moved <em>together and in a faster pace. </em>