Question

Makers of generic drugs must show that they do not differ significantly from the "reference" drugs that they imitate. one aspect in which drugs might differ is their extent of absorption in the blood. The below table gives data taken from 20 healthy nonsmoking male subjects for on pair of drugs. This is a matched pairs design. numbers 1-20 were assigned at random to the subjects. subjects 1-10 received the generic drug first, and subjects 11-20 received the reference drug first. In all cases, a washout period separated the two drugs so that the first had disappeared from the blood before the subject took the second. Do the drugs differ significantly in absorption? Describe the procedure used in testing for significance.
I tried doing a dotplot but that didn't work out too well. Am I to do the stemplot?
subj ref drub gen drug
15 4108 1755
3 2526 1138
9 2779 1613
13 3852 2254
12 1833 1310
8 2463 2120
18 2059 1851
20 1709 1878
17 1829 1682
2 2594 2613
4 2344 2738
16 1864 2302
6 1022 1284
10 2256 3052
5 938 1287
7 1338 1930
14 1262 1964
11 1438 25498
1 1738 3340
19 1020 3050

Answer 1

Answer:

Step-by-step explanation:

subj  ref drub   gen drug

1          1738            3340

2          2594          2613

3          2526            1138

4          2344           2738

5           938             1287

6           1022            1284

7             1338            1930

8            2463           2120

9           2779             1613

10           2256            3052

those are the 10 first ones, you want to calculate the mean of the absorption time for about drugs, you can do this by summing all the times and dividing it by the total of samples, in this case 10.

for the reference drug the mean is 1999.8

for the generic drug the mean is  2018.8

which says that the generic drug is absorbed a little bit slower in mean, but this may be because our samples took other one first, so now we see the other 10, i will only put the math here

for the sample drug 2097.4

for the generic drug 2240.66

where i discarded the sample number 11 because there may be a error there.

then in bout cases you can see that the generic drug is absorbed slowly.