Local anesthetics inhibit nerve conduction in a reversible manner without altering the nerve. The inhibition appears rapidly and for a longer or shorter duration depending on the products and the concentrations used. The extent of the territory rendered insensitive to pain depends on the modes of administration of the local anesthetic, either at the level of the nerve endings, or at the level of a nervous trunk, for example.
They act at the level of the neuronal membrane by interfering with the process of excitation and conduction. The anesthetic crosses the axon membrane, rich in lipids, in the form of base before taking up a cationic form on the internal face of the neuron where the pH is more acidic.
At this level, there is a blockage of nerve conduction by decreasing the membrane permeability to sodium ions that occurs during the depolarization phase. As the progression of the anesthetic action along the nerve increases, the threshold of excitability increases and the conduction time increases. This is completely blocked from a certain concentration of local anesthetic.
The nerve fibers are unequally sensitive to the action of local anesthetics: they disappear in order: the painful, thermal, tactile sensations.
Answer:
She could teach her the serious danger she could do to her body
Explanation:
she should also show her what drug do to people and how there life change how there future can be determined by that one action . Even if you try drug one time or miss use drug once it can be addicting and lead you down the wrong path. Also if you get caught the you could get suspended or even expelled and there goes your future/ dreams.
Answer:
The FDA Food Code is not federal law
Explanation:
It is the FDA's best “advice” for ways to ensure that food at retail and in foodservice is safe, properly protected and presented.
1. if the person is saying goodbye to everyone and saying sorry and how much they love them
2. if they write a note
3. when the person starts giving up on everything
4. if the person is drowning in self pity they tend to think suicidal
5. signs of being depressed or emotional outburst for no reason
