There were many famous and influential legislators in the Old South, especially in the time leading up to the Civil War, but perhaps one of the most prominent was John C. Breckinridge
John Quincy Adams was the sixth President of the United States who was the first son of a President to become President himself. Adams was a skilled diplomat who served as Secretary of State before becoming President.
The most signficant impact of the anti-federalists on the Constitution was the implementation of the Bill of Rights.
Anti-federalists were concerned that the new US Constitution gave too much power to the federal government. Anti-federalists argued that a strong central (aka federal) government would result in tyranny, just like it did when America was still part of the British empire. This is why the anti-federalists wanted a list of rights that all American citizens can possess. This list of rights would check the power of the federal government and prevent the government from restricting the rights of citizens.