Identify two general ways chemical mutagens can alter dna.

1 answer:

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1) compound mutagens can go about as base analogs
Analogs are perceived by DNA polymerase and consolidated into DNA set up of nucleotides and after that reason change by base-matching in a way that varies from the undifferentiated from nucleotide. For instance, 5-BrdU can be consolidated inverse An amid replication and after that combine as a C amid the following round of replication, making a TA CG change.
2) substance mutagens can synthetically adjust base.
Compound adjustment of bases changes their base-blending properties to such an extent that an altered purine will base-match with the wrong pyrimidine and the other way around. For instance, EMS is an alkylating operator that proselytes guanine to O6-methylguanine, which base-sets with T to make a GC to AT progress

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