First thing is Male gametes are called sperm and Female gametes are called eggs. So some physical differences are that the eggs are spherical in shape, much larger then sperm, and are immobile (they stay in the female reproductive organ during fertilization). Sperm are smaller, are in a cone shape, and have tails so the could move to the egg during fertilization.
Answer:
The type of regulation of gene expression that would have the greatest chance of success is Posttranslational control (E).
Explanation:
The defect is found on the structure of the protein, this means that the process of formation of the protein and the codons responsible for each amino acid in the protein is in correct order, this set the transcriptional and translational process aside as being correct.
Therefore, the problem lies in the formation of secondary or tertiary structure of the protein which requires a good number of proteins also, wherein lies tha main problem in the cell membrane protein. Thus the regulation of the posttranslational process and correction of the proteins needed at this stage will give the best chance of success.