Question

Archeological evidence suggests that Neanderthals might have been aware of the medicinal properties of plants over 60,000 years ago. Imagine you are a modern-day ethnobotanist and have identified a compound from fossilized tree pollen that binds to the alpha subunit of the most common G-proteins. To test how whether the compound affects the activity of Gα, you treat liver cells with the compound alongside epinephrine. You observe that the cells fail to produce glucose. Which could be the activity of the compound?

Answer 1

Answer:

It could be prevent Ga from binding to the epinephrine receptor.

Explanation:

Hindering GTPase action will make G-protein to tie to adenyl cyclase for all time so Glucose is delivered persistently.  

Diminishing the proclivity for GDP will build the opportunity of authoritative of GTP to G protein which thus will initiate the pathway.  

On the off chance that G protein ties with adenyl cyclase it will invigorate it.  

Yet, in the event that the G-protein is kept from official with epinephrine receptor, at that point the receptor can't enact trade the guanine nucleotide to G-protein for initiation. Thus the G-protein stays in latent state.