The illustration the question refers to is Death's Dispensary (1866) by George Pinwell. You can see it below.
The correct answer is 2, Victorian England.
It refers to the cholera outbreak that happened in the mid-1800s and spread worldwide. This third wave of cholera in the history of humanity is thought to have started in India. It killed more than a million people in Russia and 646 in Britain.
This outbreak pressed the government to improve the sanitation facilities of the country and impacted heavily the public health system.
George Washington did not want to accept the presidency that the people wanted to give him for fear of becoming a tyrant himself, just like King George II of England, from whom they just declared themselves independent from. When he became president, he made an example by only taking 2 terms and then refusing to continue being president. It wasn't until much later that a law was introduced to prevent any single president from serving more than 2 terms.
The increase in the trade of silver during the period between 1550 and 1800 is due to the fact that silver was started to be used as a standard currency for trade purposes. Even though it was not considered as "legal tender", as it would later be used for this purpose with the introduction "Bimetallism" in the 19th century, it was widely adopted as a tool for trade among the civilizations that existed at the time.