The false statement is: (a) Transcriptional regulators usually interact with the sugar–phosphate backbone on the outside of the double helix to determine which DNA sequence to bind.
Transcriptional regulator or factor is protein with the ability to control and regulate gene expression at the transcription level by binding to DNA. Transcriptional factors have domain-DNA-binding domain which contains structural motif that recognizes DNA and it is responsible for the attachment to specific DNA sequence. It usually binds to the DNA major groove (hydrogen bonding) because it is less degenerate than that of the DNA minor groove.
Transcriptional factors also contain trans-activating domain for the binding of other proteins and signal-sensing domain for the detection of external signals.
Answer:
Amino acid substitutions at the interaction interface may result in binding affinity changes, and thus affect the structure of the protein complex. ... This structural change may significantly affect the binding energy, and make the protein complex unstable
Explanation:
I hope it helped
Answer:
See attached image
Explanation:
Action potential can be split into 5 phases (0-4), where phase 4 leads from one action potential to the next. Phase 0 is the line up and is known as depolarization, it is here where the action potential is triggered and fast Na channels will open. Next, is phase 1 called early repolarization which is the little bit at the beginning of the plateau-here the Na channels will close. Then you have the plateau phase where Ca channels are open at the beginning and close at the end. Then is phase 3 called repolarization which is the big slope down and here is where the normal transmembrane ionic concentration gradients are restored. Finally, phase 4 which is the resting phase occurs. There are many resources online if you need more details, here is a pretty good one: http://www.pathophys.org/physiology-of-cardiac-conduction-and-contractility/
Answer:
Ii
Explanation:
Because it has one dominant allele <em>(I)</em> and one recessive allele <em>(i)</em>.
Answer: The answer is Computer Model
Many researchers have suggested that using computer models would be more advisable to use to predict the earthquake. Researchers believe that it would be easier to tell the reaction of many nuclear power plants. They want to reassess the safety measures that are being implemented by many nuclear power plants.
Explanation: