Answer:
The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.
In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.
Explanation:
The two organisms that are most closely related according to Linnaean taxonomy are <em>Felis catus</em> and <em>Panthera pardalis</em>, because they belong to the same family
<h3>What is taxonomic classification?</h3>
Linnaean system of classification consists of a hierarchy of groupings called taxon. Each taxon is arranged in a hierarchical order.
The hierarchical arrangement of the taxon are as follows:
- Kingdom
- Phylum/Division
- Class
- Order
- Family
- Genus
- Species
These taxa are arranged from the most inclusive to the most exclusive i.e. members of the same species are the most closely related in that order.
This suggests that <em>Felis catus</em> and <em>Panthera pardalis</em> are the most closely related because they belong to the same family.
Learn more about Linnean classification at: brainly.com/question/2321636
#SPJ1
<span> Gemini will be visible almost 9 months, Other times it will be visible at night sometimes, due to the earths rotations only certain constellations are see able at one time. </span>
Ye because ur looking at a grossly bear very scary and also it can bite u so hard that ur brain is gonna splatter everywhere into tiny bits of chunks
