Such a substitution could: change a codon to one that encodes a different amino acid and cause a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.
Explanation:
For example, sickle cell anemia is caused by a substitution
It is important that it has half because there is a half that comes from each parent. so to equal it all out human gametes have a half set of dna instead of a full set
