Question

Which of the following is directly involved in driving protein import into the mitochondrial matrix space? A. GTP hydrolysis outside mitochondria B. Membrane potential across the outer membrane C. Light D. ATP hydrolysis inside mitochondria E. GTP hydrolysis inside mitochondria

Answer 1

Answer:

The correct answer is D; ATP hydrolysis inside mitochondria

Explanation:

Proteins imports brought into the matrix of mitochondria are normally taken up from the cytosol in practically less time after their discharge from ribosomes. Transportation of protein imports into the matrix is driven by energy which is supplied by:

• ATP hydrolysis outside the mitochondra: this occurs in the first step of translocation process. ATP hydrolysis drives the release of newly synthesized polypeptides from the hsp70 group of chaperone proteins.

• an electrochemical proton gradient across the inner mitochondrial membrane maintained by electron transport process in the inner membrane.

• ATP hydrolysis in the matrix: Hsp70 chaperone proteins in the matrix space likewise have a job in the translocation procedure, and they are the third point in the import procedure at which ATP is expended.