Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Storing energy because it’s not with the other energy
One of the differences between the cell membrane and the cell wall is in the type of organisms that they are found in. A cell wall is found in plants only. A cell membrane is found in all organisms including plants. Present only in plants, and in some fungi, bacteria, algae.
Answer:
Cell–cell interaction
Explanation:
Based on the scenario being described it can be said that the developmental process that has most likely been affected are known as Cell–cell interaction. These are the direct interactions that exist between cell surfaces that allow them to communicate with one another. Doing so by receiving signals and initiating transduction pathways. Therefore since these are functions that have been disrupted it's safe to say that the Cell-cell interaction has been affected.
Answer:
false
Explanation:
this goes for identical twins: identical twins can have the same level of gene within the genome but they are genetically not identical.
this is due to different stages of cell division that occur during embryo development.