Answer:
Citrate Synthase facilitates the formation of citrate by deprotonating Acetyl CoA and by protonating the carbonyl oxygen of oxaloacetate
Explanation:
Citrate synthase is a key enzyme in the citric acid cycle that functions to catalyze the formation of citrate from oxaloacetate and acetyl-CoA: acetyl-CoA + oxaloacetate + H2O >> citrate + CoA-SH (Coenzyme A ). This enzyme contains three amino acids at its active site that work together to catalyze the conversion of acetyl-CoA and oxaloacetate into citrate. This active site acts by abstracting (deprotonating) a proton from the alpha carbon of Acetyl CoA which serves as the nucleophile. Subsequently, the active site of the enzyme also protonates the carbonyl oxygen of oxaloacetate, which then suffers nucleophilic attack and thereby facilitating nucleophilic substitution reaction.
Answer:
A generation is "all the people who are born and lived at about one time collectively" and is also defined as "the average period in which children are born and grow up, becoming adults and start having children of their own" "currently approximately thirty years"
Four conditions are needed for natural selection to occur: reproduction, heredity, variation in fitness or organisms, variation in individual characters among members of the population. If they are met, natural selection automatically results.
