Answer:
DNA vaccines consist of DNA vectors or plasmids (small double-stranded DNA rings originally derived from bacteria, but unable to cause infection) into which the genes encoding one or more immunizing proteins of the infectious agent have been inserted causing the disease to be prevented.
Explanation:
Vectors are the functional unit of naked DNA vaccines. Genes that encode the proteins of interest and are of bacterial origin are inserted into these vectors. Bacterial plasmids are circular DNA molecules that self-replicate extrachromosomally in bacteria. The genes encoded in these plasmids are under the control of promoters, almost always of viral origin. When a plasmid is introduced into the cell it translocates to the nucleus, where transcription of the transgene begins; the transcripts are then taken to the cytoplasm and translated there. The newly synthesized proteins are degraded in the proteasome to 8-10 amino acid peptides, which are transported to the endoplasmic reticulum. Peptides of high affinity with their respective MHC I molecule stabilize and enter the secretory pathway, thus reaching the cell surface, where they are coupled with the T-lymphocyte receptor (TcR) present on the surface of T lymphocytes cytotoxic drugs (CD8 +) to induce their activation.
The cell theory consists of:
1. all living organisms are made up of cells
2. cells are the basic structural/organizational unit of all organisms
3. all cells come from pre-existing cells
Mitosis is the division that results in two “daughter” cells. Both of these daughter cells have the same number of chromosomes as the “parent” cell.
Mitosis consists of 4 phases: prophase, metaphase, anaphase, and telophase.
Prophase: the DNA is copied and the chromosomes pair up
Metaphase: the chromosomes line up in the middle of the cell
Anaphase: sister chromatids are pulled apart from each other towards opposite sides of the cell
Telophase: the cell begins to pinch in the middle and separates into two identical daughter cells
You would expect to find a <span>plasma membrane </span>
