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irga5000 [103]
3 years ago
8

When NAD+ becomes NADH, it is being

Biology
1 answer:
ipn [44]3 years ago
5 0

NAD+ accepts a hydrogen ion (H+) and two electrons (2e−), as it becomes reduced to NADH + H+. The NADH moves to the electron transport chain and donates a pair of electrons (becomes oxidized) to the first compound in the chain.

Explanation:

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DCCD (dicyclohexylcarbodiimide) inhibits oxidative phosphorylation when the substrate is mitochondrial NADH. DCCD is a drug that
VARVARA [1.3K]

Answer:

A) Decreases cellular energy production

B) DCCD also affects K+ transport

Explanation:

A) Consequences are of DCCD on cellular energy production: <em>Decreases cellular energy production</em>

ATP-synthase pump is composed of two subunits: F1 catalytic subunit that synthesizes ATP, and F0 proton pumping subunits, that transport H+ through the membrane. F1 subunit might act independently of F0 to produce ATP, but this molecule can not be released without H+ gradient, which generates a movement necessary for ATP release from the catalytic center.

When any of the parts composing F0 react with DCCD, the subunit can not transport H+ through the membrane. DCCD inhibits the enzyme activity by blocking the protons´ flow.

As DCCD blocks the protons´ flow, and the protons´ flow is necessary to release the ATP molecule from the F1 subunit, no other ADP + Pi can enter to F1 subunit, and the production of ATP stops.

B) Other cellular effects of DCCD

There seem to be other effects of DCCD on cell activity, some of which are still under study. To name a few:

  • Diimide from DCCD seems to stimulate cytochrome b reduction and inhibits its reoxidation by ferricyanide.
  • When exposing the cell to high concentrations of DCCD for a long time, might occur an alteration in the electron transporting chain
  • Inhibition of ubiquinol-cytochrome c reductase activity when exposing the cell to high concentrations of DCCD.
  • Inhibition of K+ transport, associated with the inhibition of H+ transport.

Concerning the effect of DCCD on the K+ transport, DCCD stops the extrusion of H+ and the consequent intrusion of K+.

DCCD strongly inhibits the simultaneous flow of H+ and K+. First, it inhibits H+ flow, acidification of the environment stops, but at this point, K+ keeps moving through the membrane. Once the H+ flow has ceased, the K+ flow slowly decreases until it finally stops moving. There is a lag time in the DCCD effect on K+ flow to the instantaneous effect on H+ flow.

5 0
3 years ago
10) Why do viruses need living hosts, such as bacteria or eukaryote cells? A) The host cell is the source of food for the virus.
bija089 [108]

B.) is 100% correct

7 0
3 years ago
What instrument developed in the 1600’s led to the discovery of additional objects other than the five planets, Mercury, Venus,
MrRissso [65]

Answer:

Telescope also known as "spyglass"

Explanation:

In 1609, using this early version of the telescope, Galileo became the first person to record observations of the sky made with the help of a telescope. He soon made his first astronomical discovery.

7 0
3 years ago
Which property is shared by the cells of all living things?
Vinvika [58]

Answer:

cells, growth, reproduction, adaptation, homeostasis, use of energy and response to the environment

6 0
3 years ago
Does thymus aid the immune system
DedPeter [7]

thymus plays important role by development of a normal, healthy immune system. thymus function is to generate mature lymphocytes

In other words, white blood cells that help fight of illness in the immune system.

sorry if I am wrong.

4 0
3 years ago
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