Interrupt, rupture
contradict, verdict
respect, import
deport, inspect, transport
This is what I got. I hope this helps :)
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
Answer:
The correct answer is: False.
Explanation:
- A Fishery collapse can be defined as the condition in which the composition of different species of fishes forming a food chain or a food web and located in a marine or aquatic community undergoes a drastic alteration.
- The alternation can be caused due to environmental or anthropological factors.
- A fishery collapse usually affects the larger fish population like sharks and tuna as their commercial and economic demand is higher.
- Excessive fishing cause the population of the large fishes to decline without affecting the small fish population.
- This is because the small fishes do not have high economic or commercial demand, hence they have very less probability of being angled or captured.
Its A. it prevents sperm from reaching the egg and fertilizing it.
If the Calvin cycle slows down, THE RATE OF OXYGEN PRODUCTION IN PS II WILL BE REDUCED.
This is because, the light reaction depends on the dark reaction to occur. If the Calvin cycle slows down, the light cycle will have less ADP and NADP+ to work with and this will slow down the production rate of the photosynthetic reaction.
