Answer:
The best evidence for the three domain system is
Sensitivity to Antibiotics
Explanation:
The three domains of life includes :
Archaea - oldest known domain, ancient forms of bacteria.
Bacteria - all other bacteria that are not included in the Archaea domain.
Eukarya - all the organisms that are eukaryotic or contain membrane-bound organelles and nuclei.
Types of evidences for the three domain system are:
1) differences in the sequences of nucleotides in the cell's robosomal RNAs (rRNA)
2) the cells's membrane lipid structure.
3) its sensitivity to antibiotics.