Answer:
The human body needs a list of macromolecules and micromolecules for performing day to day functions.
The essential macronutrients that the body requires are:
Carbohydrates: Carbohydrates are required by the cells in the body to carry out normal day to day functions. Energy is provided in the form of calories by the carbohydrates.
Proteins: Proteins are essential nutrients which are required for growth as well as better functioning of the immune cells of the body.
Fats and oils: These are needed for providing insulation to the body and to store energy.
Fibres: These are a mixture of carbohydrates.
Water: Almost every activity of the body requires water.
The essential micronutrients that the body requires are:
Vitamins: Vitamins are a group of substances which are needed by the body to function normally.
Minerals: Mineral are needed to ensure that tissues are working correctly.
luconeogenesis is a ubiquitous process, present in plants, animals, fungi, bacteria, and other microorganisms.[2] In vertebrates, gluconeogenesis takes place mainly in the liver and, to a lesser extent, in the cortex of the kidneys. In ruminants, this tends to be a continuous process.[3] In many other animals, the process occurs during periods of fasting, starvation, low-carbohydrate diets, or intense exercise. The process is highly endergonic until it is coupled to the hydrolysis of ATP or GTP, effectively making the process exergonic. For example, the pathway leading from pyruvate to glucose-6-phosphate requires 4 molecules of ATP and 2 molecules of GTP to proceed spontaneously. Gluconeogenesis is often associated with ketosis. Gluconeogenesis is also a target of therapy for type 2 diabetes, such as the antidiabetic drug, metformin, which inhibits glucose formation and stimulates glucose uptake by cells.[4] In ruminants, because dietary carbohydrates tend to be metabolized by rumen organisms, gluconeogenesis occurs regardless of fasting, low-carbohydrate diets, exercise, etc.[5]
Addition or deletion of nucleotides in any number besides 3 results in a "frame-shift mutation."
This is because every 3 nucleotides of DNA/mRNA exons codes for a single amino acid in the synthesis of a protein. This triplet codon theory means that if 3 nucleotides are added or deleted then an amino acid will be added or lost, but subsequent codons and amino acids will still be read correctly.
However, if any number of nucleotides other than 3 are added or removed, then the codons following the mutation will be out of "sync," in terms of the reading order.
Hence it is called a frame-shift mutation because it shift the reading frame when translating nucleic acids into proteins. Frame shifts will lead to the wrong amino acids being adding in the wrong order for the rest of the code after the mutation.
