1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Lera25 [3.4K]
3 years ago
8

A nurse has been administering a drug to a client intramuscularly (im). the health care provider discontinued the im dose and wr

ote an order for the drug to be given orally. the nurse notices that the oral dosage is considerably higher than the parenteral dose and understands that this due to:
Biology
1 answer:
ludmilkaskok [199]3 years ago
5 0
First-pass effect.

  
The first-pass effect involves drugs that are given PO and absorbed from the small intestine directly into the portal venous system, which delivers the drug molecules to the liver. Once in the liver, enzymes break the drug into metabolites; they may become active or may be deactivated and readily excreted from the body. A large percentage of the oral dose is usually destroyed and never reaches tissues. Oral dosages account for this phenomenon to ensure an appropriate amount of the drug in the body to produce a therapeutic action. Passive diffusion is the major process through which drugs are absorbed into the body. Active transport is a process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney. Glomerular filtration is the passage of water and water-soluble components from the plasma into the renal tubule.
You might be interested in
If the amount of predators in the mice environment increased, the mices carrying capacity would_____. (Increase/Decrease). Becau
Vaselesa [24]

Answer: Decrease, i'm sorry i don't know the other one

Explanation:

3 0
2 years ago
Please Help<br> Sex-Linked Disorder
Masteriza [31]

Explanation:

hemopholia

colour blindness

8 0
3 years ago
Which of the following steps in prokaryotic binary fission is correct?
elixir [45]
Hi lovely,

Are you able to provide me with your answer choices?
4 0
3 years ago
which biomolecule provides building ,transports other molecules and helps regulate certain reactions in the human body?
kramer

This would be enzymes made of proteins.

If you appreciated my answer, please brainliest me!

5 0
3 years ago
Explain how biodiversity affects ecosystem services.
Kipish [7]

<h2>ecosystem services provided by biodiversity, such as nutrient cycling, carbon sequestration, pest regulation and pollination, sustain agricultural productivity. Climate change and other stresses have the potential to make major impacts on key functions, such as pollination and pest regulation services.</h2><h2 />
8 0
2 years ago
Other questions:
  • In fertilization, fertilization occurs within the body of the female
    15·2 answers
  • Which best describes why sexual reproduction, and not merely asexual reproduction, is necessary for the evolutionary process?
    14·1 answer
  • How does exercise benefit the cardiovascular system
    11·1 answer
  • Climate change is having a great impact on the Arctic food web on land and on the ice. The animals most at risk from a warming p
    15·1 answer
  • The Northern and Southern Hemispheres experience opposite seasons and different day lengths, no matter what time of year. What i
    5·2 answers
  • Which phase of mitosis is shown in the diagram?
    7·2 answers
  • Which color has the shortest wavelength
    11·2 answers
  • Define SELECTIVE BREEDING in your own words
    14·1 answer
  • NEED HELP! PLS 40 POINTS REWARD
    5·1 answer
  • Suggest a reason why termites have no eyes
    7·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!