A “This debt we pay to human guile” ( Line 3)
Explanation:
From the poem, the writer is trying to justify the use of masks to hide our sorrows from the world so that it won't see our bleeding hearts and mouths that have been lots of "subtleties".
The central idea of the poem is to wear the mask and disguise our true feelings to the world while we pay the debt of not showing our true feelings to people that matter to us.
Answer:
Multiple sclerosis (MS) is the most common demyelinating and an autoimmune disease of the central nervous system characterized by immune-mediated myelin and axonal damage, and chronic axonal loss attributable to the absence of myelin sheaths. T cell subsets (Th1, Th2, Th17, CD8+, NKT, CD4+CD25+ T regulatory cells) and B cells are involved in this disorder, thus new MS therapies seek damage prevention by resetting multiple components of the immune system. The currently approved therapies are immunoregulatory and reduce the number and rate of lesion formation but are only partially effective. This review summarizes current understanding of the processes at issue: myelination, demyelination and remyelination—with emphasis upon myelin composition/architecture and oligodendrocyte maturation and differentiation. The translational options target oligodendrocyte protection and myelin repair in animal models and assess their relevance in human. Remyelination may be enhanced by signals that promote myelin formation and repair. The crucial question of why remyelination fails is approached is several ways by examining the role in remyelination of available MS medications and avenues being actively pursued to promote remyelination including: (i) cytokine-based immune-intervention (targeting calpain inhibition), (ii) antigen-based immunomodulation (targeting glycolipid-reactive iNKT cells and sphingoid mediated inflammation) and (iii) recombinant monoclonal antibodies-induced remyelination.Keywords: calpain, central nervous system, demyelination, fingolimod, glycolipids, lipids, multiple sclerosis, myelin, myelination, NKT cells, oligodendrocytes, remyelination, T cells
Explanation:
Explanation:
The endocrine hormones help control mood, growth and development, the way our organs work, metabolism , and reproduction. The endocrine system regulates how much of each hormone is released. This can depend on levels of hormones already in the blood, or on levels of other substances in the blood, like calcium.
Without your endocrine glands — and the hormones they release — your cells wouldn't know when to do important things. For instance, your bones wouldn't get the message that it's time for you to grow and get bigger.
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Answer:
"50%, so you are correct, legislation can lead to significant positive health outcomes."
Explanation:
Health and safety legislation. Safe exercise is very significant to the raise of self-respect in care. There are a few governmental procedures and rules to care health and safety at work. These are planned to defend people in work, those by means of facilities and the broader public. Legislation is one of the most significant tools of administration in organizing society and defending citizens. It controls between others the privileges and tasks of persons and establishments to whom the legislation applies
I say it is a because it is important to maintain a healthy weight plan