You are interested in studying a receptor and decide to make a knockout mouse. However, you notice severe developmental defects
that result in embryonic lethality in this receptor knockout. Which developmental process is most likely affected when you disrupt a receptor on the cell surface, disrupting its ability to receive a signal and initiate a transduction pathway?a. apoptosis cell b. proliferation cellc. cell interactions d. cell movement e. cell differentiation
The correct answer is option c. "cell interactions".
Explanation:
Cell-to-cell interactions, or only cells interactions, refers to the mechanisms that cells have to communicate among them. These mechanisms takes place at the surface of the cells by sending and receiving signals in receptors, which later initiate transduction pathways. Cell interactions play a crucial role in the development of embryos, therefore if a knockout mouse has embryonic lethality due to a disruption in a receptor, it is very likely that the development process that is affected is related with cell interactions.
