Interesting biology question.
In order to answer this question, I hope you understand what is mitosis: cell division that creates two diploid "daughter" cells that are identical to each other. Gametes, remember, are the reproductive cells (egg cells and sperm).
If human gametes were made by mitosis, which is not true, because gametes are made in meiosis, they would simply be diploid with somatic cells. The two gametes would have 92 chromosomes, as each cell has 46 chromosomes. And after each generation, the number of chromosomes would keep doubling, which would be very weird. Remember that the normal amount of chromosomes that a human being has, is 46. Maybe humans would have mutations if that happened.
I'm pretty sure it's high density as a solid.
The hole is a separate phenomenon because it correlates something other than global warming. it doesn’t focus on global warming but more on specific areas.
An agonist exhibit a positive biological effect similar to the receptor it stimulates. For instance, beta agonists (i.e. Salbutamol) stimulate the beta receptors in the bronchial system therefore leading to bronchodialtion. A competitive antagonist negates the function of the specific receptor by binding to the receptor binding site before the biological ligand. A non-competitive agonist negates the function of the specific receptor by binding to an allosteric site leading to a conformational change of the receptor site.