Answer:
The C. elegans embryo is a powerful model system for studying the mechanics of metazoan cell division. Its primary advantage is that the architecture of the syncytial gonad makes it possible to use RNAi to generate oocytes whose cytoplasm is reproducibly (typically >95%) depleted of targeted essential gene products via a process that does not depend exclusively on intrinsic protein turnover. The depleted oocytes can then be analyzed as they attempt their first mitotic division following fertilization. Here we outline the characteristics that contribute to the usefulness of the C. elegans embryo for cell division studies. We provide a timeline for the first embryonic mitosis and highlight some of its key features. We also summarize some of the recent discoveries made using this system, particularly in the areas of nuclear envelope assembly/ dissassembly, centrosome dynamics, formation of the mitotic spindle, kinetochore assembly, chromosome segregation, and cytokinesis.
1. The C. elegans embryo as a system to study cell division
The C. elegans embryo is a powerful model system for studying the mechanics of metazoan cell division. Its primary advantage is that the syncytial gonad makes it possible to use RNA interference (RNAi) to generate oocytes whose cytoplasm is reproducibly (>95%) depleted of targeted essential gene products. Introduction of dsRNA rapidly catalyzes the destruction of the corresponding mRNA in many different systems. However, depletion of pre-existing protein is generally a slow process that depends on the half-life of the targeted protein. In contrast, in the C. elegans gonad, the protein present when the dsRNA is introduced is depleted by the continual packaging of maternal cytoplasm into oocytes (Figure 1). Since depletion relies on the rate of embryo production instead of protein half-life, the kinetics tend to be similar for different targets. By 36-48 hours after introduction of the dsRNA, newly formed oocytes are typically >95% depleted of the target protein.
Explanation:
When someone does not have insurance:
• Infected patient with contagious disease won’t be treated so the infection might be spread,
• Emergency treatment and care for uninsured patient will cost a lot more than for the patient with insurance,
• Staying in hospital rooms and using hospital resources is more expensive.
Answer: warm front
Explanation: When a warm air mass meets a cold air mass, the warm air rises since it is lighter. At high altitude it cools, and the water vapor it contains condenses. This type of front is called a warm front. It generates nimbostratus clouds, which can result in moderate rain.
Answer/Explanation:
Cells of a similar type are organized together to make tissues. Different types of tisues come together to perform a similar function as part of organs.
For example, take the organ the stomach. There are various tissues that make up the stomach, including, for example, mucosa, and muscle tissue.
The mucosa tissue of the stomach is made up of secretory cells such as parietal cells, which secrete hydrochloric acid, and foveolar cells which produce mucus that protects the lining of the stomach.
Because it can analyze of what we are made of and who were our ancestors by studying our DNA
