<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
Answer:
Guppies would become more colorful.
Explanation:
Outer hair cells change their axial dimensions in response to electrical stimulation.
What is basilar membrane motion?
Hair cell stereocilia move as a result of the basilar membrane's movement. The tectorial membrane and the hair cells, which are connected to the basilar membrane, move along with it when it moves, and the stereocilia bend in response to the relative motion of the tectorial membrane.
The hair cells that are linked to the auditory nerve fibers are stimulated by the basilar membrane's movement. While the outside hair cells actively affect the basilar membrane's vibrations, the inner hair cells convert hydromechanical vibration into action potentials.
With each sound cycle, the intracellular voltage of the outer hair cells varies, causing them to lengthen and contract. This increases the organ of Corti's vibration, enabling exceptionally high hearing sensitivity and frequency selectivity.
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The question that Charles Darwin would be prompted to ask on his voyage is as follows: can selection in nature also lead to a new species over time?.
<h3>Who is Charles Darwin?</h3>
Charles Darwin was a British naturalist/scientist and founder of the theory of evolution by natural selection.
He is best known for his award-winning work on the origin of species, which he published in 1859. Darwin developed his theory from findings he made following a five-year expedition on board HMS Beagle.
According to this question, Darwin reviewed his observations after he returned home from his voyage studying the selective breeding of pigeons.
The question that Charles Darwin would be prompted to ask on his voyage is as follows: can selection in nature also lead to a new species over time?.
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