Which molecule controls the rate of the pentose phosphate pathway? glucose ribose 5‑phosphate ADP / ATP NADP + / NADPH NAD + / N
ADH Which reaction is influenced by the molecule in the first question? Choose the enzyme that catalyzes the reaction. (This is the major controlling step.) a. transketolase b. transaldolase c. phosphopentose epimerase d. glucose 6‑phosphate dehydrogenase e. phosphopentose isomerase f. lactonase
Answer: NaDP+/NaDPH and D. glucose 6‑phosphate dehydrogenase
Explanation:
Pentose Phosphate pathway could be generally divided into oxidative and non-oxidative. The rate-limiting irreversible step in the oxidative step defined by the glucose-6-phosphate dehydrogenase which requires the reduction of NADP to NADPH. The enzyme is highly selective for the NADH and its activity is tightly dependent on the presence of the NADP
