Hardy Weinberg Equilibrium
Explanation:
- Hardy Weinberg Equilibrium formula for allelic frequency is:
- Hardy Weinberg Equilibrium formula for genotypic frequency is:
- Here,
=frequency of dominant allele
=frequency of recessive allele
=frequency of dominant genotype
=frequency of recessive genotype
=frequency of heterozygous genotype
- frequency of affected individuals=0.0004(given)
here,affected individuals means the one's having Cystic Fibrosis and since it is recessive disease so we can write frequency of recessive genotype as: =0.0004
- If
=0.0004
will be 0.02;frequency of recessive allele will be 0.02
- Using the formula
- hence,frequency of dominant allele will be 0.98
- Frequency of dominant genotype will be
- Frequency of heterozygous genotype will be