The acidic environment of the lysosome and the lysosomal enzymes detach the ligands from their receptors.
Receptor-mediated endocytosis is a process in which cell surface receptors are employed for transporting substances such as proteins, hormones, and metabolites from extra-cellular matrix into the cells. Receptor-mediated endocytosis usually occurs through clathrin (a type of protein)-coated pits and vesicle and it allow only the receptor-specific substances to enter the cell. Under this process, molecule binds to protein receptors after which the receptor molecule moves to clathrin coated pits and vesicle. The cell membrane then folds inwards and there is fusion of a coated vesicle. After this, the ligands are detached from their receptors.
<span>ER Golgi apparatus, because it packages proteins received from the ER cytoplasm </span>
<span>The Golgi body are the ones that slightly alter, organize and prepare so-called parcels to be delivered for all the organelles in the cell. They receive these packages mainly in the rough endoplasmic reticulum. These packages that set out by Golgi body are macromolecules that used and synthesized by cells in many operations. If ER is absent then it would only mean that Golgi body would have no use other than simply lysosomes but these macromolecules plays a dynamic role in many organelles –nutrients, ATP and cell metabolism. It'll have a ripple effect if ER is absent in the cell.<span> </span></span>
At The Middle Stage We Get More Pleasure........!!!!!!
Animals because that is not part of a cell house
