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NEWS
What Happens to Tumor Cells After They Are Killed?
Oncology Times: December 25, 2017 - Volume 39 - Issue 24 - p 46-47
doi: 10.1097/01.COT.0000528040.85727.60
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tumor cells: tumor cells
Researchers from Harvard Medical School, Boston, and the Institute for Systems Biology, Seattle, have discovered that the remains of tumor cells killed by chemotherapy or other cancer treatments can actually stimulate tumor growth by inducing an inflammatory reaction. The study also reveals that a family of molecules called resolvins can suppress this unwanted inflammatory response, suggesting new ways to enhance the effectiveness of existing cancer therapies
Conventional, radiation- and drug-based cancer therapies aim to kill as many tumor cells as possible, but the debris left behind by dead and dying cancer cells can stimulate the production of proinflammatory cytokines, signaling molecules that are known to promote tumor growth.
“Dead and dying tumor cells are an underappreciated component of the tumor microenvironment that may promote tumor progression,” explained Charles N. Serhan, PhD, Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital and Professor at Harvard Medical School. Serhan and colleagues therefore decided to investigate whether tumor cell debris can stimulate tumor growth.
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D) She should look at her notes to find an example that shows exactly why she disagrees.
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4
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Because all the living things need carbon to make protein,carbohydrates,lipids
The Best Answer :
<span>"G2 phase is the third, final, and usually the shortest subphase during interphase within the cell cycle in which the cell undergoes a period of rapid growth to prepare for mitosis. It follows successful completion of DNA synthesis and chromosomal replication during the S phase, and occurs during a period of often four to five hours. This far into interphase the nucleus is well defined, bound by a nuclear envelope and contains at least one nucleolus. Although chromosomes have been replicated they cannot yet be distinguished individually because they are still in the form of loosely packed chromatin fibers. The G2 phase prepares the cell for mitosis (M phase) which is initiated by prophase.
At the end of this gap phase is a control checkpoint (G2 checkpoint) to determine if the cell can proceed to enter M phase and divide. The G2 checkpoint prevents cells from entering mitosis with DNA damaged since the last division, providing an opportunity for DNA repair and stopping the proliferation of damaged cells. Because the G2 checkpoint helps to maintain genomic stability, it is an important focus in understanding the molecular causes of cancer."</span>
