I believe it was the civil rights act of 1964.
Article I, Section 4, Clause 1: The Times, Places and Manner of holding Elections for Senators and Representatives, shall be prescribed in each State by the Legislature thereof; but the Congress may at any time by Law make or alter such Regulations, except as to the Places of chusing Senators.
The correct answer is 2. Isolationism
Following world war 1, United States didn't want to mess with European affairs because they understood how bad the war was and didn't want to participate in it again. That's why when Wilson wanted to join the League of Nations they declined and the US remained on its own.
It didnt provide slave labor for the large farming estates