From what i know, in sickle cell anemia the blood is lack of oxygen.
The haemoglobin run from the blood cell because reacted with nitric oxide, and so thats why the shape of the blood change into sickle-shaped like.
The answer is pancreas and intestinal gland. The pancreas mainly secrete amylase, to digest carbohydrates, lipase, to digest fat, and protease, to digest protein. And the intestinal gland mainly secrete carbohydrase, to digest Maltose to glucose, and protease.
Sleeping, walking, blood pressure and body tempature