Answer:
The particularly severe winter of 1777-1778 proved to be a great trial for the American army, and of the 11,000 soldiers stationed at Valley Forge, hundreds died from disease. However, the suffering troops were held together by loyalty to the Patriot cause and to General Washington, who stayed with his men.
DNA model given by Watson and Creek in the year of 1953 gave a very detailed study regarding the structure of B DNA which is valid till date and is essentially corroborating with Chargaff's data and Xray diffraction pattern.
<h3><u>Explanation:</u></h3>
The DNA is the most common nucleic acid found in the living organisms as a genetic material. As stated by Watson and Creek, this DNA contains a double helical structure with two sugar phosphate backbones and the nitrogen bases getting projected from it inwards. The backbones are formed of ribose sugar and phosphate and joined together with a phosphodiester bond. The ribose sugar is attached to phosphates at its 3' and 5' Carbon atoms. The nitrogen bases found in DNA are Adenine, Guanine, Thymine and Cytosine. The Adenine has two hydrogen bonds with thymine and guanine has 3 hydrogen bonds with cytosine.
Each full turn of a helix is 34A and each base pair is 3.4A apart. The distance between two strands of DNA is 20A.
Chargaff's rule regarding the equal amount of adenine and thymine as well as guanine and cytosine is matching with this structure. All the other rules also do match with this DNA structure.
<span>This result is produced by the selective permeability of the plasma membrane when the presence of negatively charged ions does not diffuse into the cell and the action of several sodium-potassium pump units causes an unequal distribution of charges through the membrane.</span>
The nicotine indirectly inhibit the CB1 or also known as the
Cannabinoid receptor type 1, which is the one responsible in obesity and
metabolic syndrome, thus, this would explain the weight gain associated with
people who quit smoke as if this is indirectly inhibited, it produces weight
gain.
