Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
Answer:
Water molecules will move from the side of higher concentration to the side de of lower concentration until both solutions are isotonic at this point the equilibrium will be reached.
In the plant, when a cell divides into two daughter cells, we observe in this experiment Mitosis, which is the cell division that allows the plant to elongate and occurs in the meristematic tissues that are at the ends of the plants. Whereas meiosis is restricted to reproductive tissue and forms gametes that will form new seeds through fertilization, carrying genes from one generation to another.
<h3>How does mitosis occur in plant cells?</h3>
In plant cells, division takes place from the inside out – centripetal cytokinesis. In plant cells, cytokinesis is centrifugal, from the outside to the inside: there is the formation of a lamella, which grows from the center to the periphery and separates the two cells.
With this information, we can conclude that through successive mitotic divisions that the zygote (cell generated after the meeting of gametes) manages to originate all the cells of its organism. Mitosis, therefore, is responsible for the growth and development of embryos.
Learn more about Mitosis in brainly.com/question/26678449
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Pairs of Unit Factors, or Genes
Mendel proposed that paired unit factors of heredity were transmitted faithfully from generation to generation by the dissociation and reassociation of paired factors during gametogenesis and fertilization, respectively. After he crossed peas with contrasting traits and found that the recessive trait resurfaced in the F2 generation, Mendel deduced that hereditary factors must be inherited as discrete units. This finding contradicted the belief at that time that parental traits were blended in the offspring.
A gene is made up of short sections of DNA that are contained on a chromosome within the nucleus of a cell. Genes control the development and function of all organs and all working systems in the body. A gene has a certain influence on how the cell works; the same gene in many different cells determines a certain physical or biochemical feature of the whole body (e.g., eye color or reproductive functions). All human cells hold approximately 21,000 different genes.
Genetics is the science of the way traits are passed from parent to offspring. For all forms of life, continuity of the species depends upon the genetic code being passed from parent to offspring. Evolution by natural selection is dependent on traits being heritable. Genetics is very important in human physiology because all attributes of the human body are affected by a person’s genetic code. It can be as simple as eye color, height, or hair color. Or it can be as complex as how well your liver processes toxins, whether you will be prone to heart disease or breast cancer, and whether you will be color
